Andrey Mozhaev
- Associate Professor:Faculty of Biology and Biotechnology / Joint Department with RAS Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry
- Andrey Mozhaev has been at HSE University since 2022.
Education and Degrees
- 2019
Candidate of Sciences* (PhD)
- 2010
Master's
Perm State Technical University - 2008
Bachelor's
Perm State Technical University
According to the International Standard Classification of Education (ISCED) 2011, Candidate of Sciences belongs to ISCED level 8 - "doctoral or equivalent", together with PhD, DPhil, D.Lit, D.Sc, LL.D, Doctorate or similar. Candidate of Sciences allows its holders to reach the level of the Associate Professor.
Courses (2023/2024)
- Cell Biology: the Basics of Bioprocesses (Bachelor’s programme; Faculty of Biology and Biotechnology; 1 year, 3, 4 module)Rus
- Past Courses
Courses (2022/2023)
Publications24
- Article Ryabinina A., Bryk A., Blagonravov M., Goryachev V., Mozhaev AA, Ovechkina V. Circadian Rhythms of Body Temperature and Locomotor Activity in Spontaneously Hypertensive Rats under Frequent Changes in Light Conditions // Pathophysiology. 2024. Vol. 31. No. 1. P. 127-146. doi
- Article Gordienko A., Dadinova L., Petoukhov M., Mozhaev AA, Manuvera V., Lazarev V., Shtykova E. Oligomerization of the IHF Protein in the Presence of Metal Cations // Crystallography Reports. 2024. Vol. 69. No. 2. P. 206-213. doi
- Article Chesnokov Y., Kamyshinsky R., Mozhaev AA, Shtykova E., Vasiliev A., Orlov I., Dadinova L. Morphological Diversity of Dps Complex with Genomic DNA // International Journal of Molecular Sciences. 2023. Vol. 24. No. 10. P. 8534. doi
- Article Dadinova L., Petoukhov M., Gordienko A., Manuvera V., Lazarev V., Rakitina T., Mozhaev A.A., Peters G., Shtykova E. Nucleoid-Associated Proteins HU and IHF: Oligomerization in Solution and Hydrodynamic Properties // Biochemistry (Moscow). 2023. Vol. 88. No. 5. P. 640-654. doi
- Article Gordienko A., Mozhaev A.A., Gibizova V., Dadinova L. An Anomalous Small-Angle X-Ray Scattering Study of the Formation of Iron Clusters in the Inner Cavity of the Ferritin-Like Protein Dps // Moscow University Physics Bulletin. 2022. Vol. 77. No. 6. P. 858-867. doi
- Article Shtykova E., Petoukhov M., Mozhaev AA. Formation of Iron Oxide Nanoparticles in the Internal Cavity of Ferritin-Like Dps Protein: Studies by Anomalous X-Ray Scattering // Biochemistry (Moscow). 2022. Vol. 87. No. 6. P. 511 - 523. doi
- Article Chesnokov Y., Mozhaev A., Kamyshinsky R., Gordienko A., Dadinova L. Structural Insights into Iron Ions Accumulation in Dps Nanocage // International Journal of Molecular Sciences. 2022. Vol. 23. No. 10. Article 5313. doi
- Article Erokhina T., Ryazantsev D., Samochvalova L., Mozhaev AA, Orsa A., Zavriev S., Morozov S. Activity of Chemically Synthesized Peptide Encoded by the miR156A Precursor and Conserved in the Brassicaceae Family Plants // Biochemistry (Moscow). 2021. Vol. 86. No. 5. P. 551-562. doi
- Article Batishchev O., Kuzmina N., Mozhaev AA, Goryashchenko A., Mileshina E., Orsa A., Bocharov E., Deyev I., Petrenko A. Activity-dependent conformational transitions of the insulin receptor–related receptor // Journal of biological chemistry. 2021. Vol. 296. P. 100534. doi
- Article Goryashchenko A., Pakhomov A., Ryabova A., Romanishkin I., Maksimov E., Orsa A., Serova O., Mozhaev AA, Maksimova M., Martynov V., Petrenko A., Deyev I. FLIM-Based Intracellular and Extracellular pH Measurements Using Genetically Encoded pH Sensor // Biosensors. 2021. Vol. 11. No. 9 doi
- Article Orsa A., Goryashchenko A., Serova O., Mozhaev AA, Martynov V., Pakhomov A., Svirshchevskaya E., Petrenko A., Deyev I. Generation and Characteristics of Genetically Encoded Fluorescent Sensors of Extracellular pH // Russian Journal of Bioorganic Chemistry. 2021. Vol. 47. No. 5. P. 1060-1065. doi
- Article Dubrovin E., Dadinova L., Petoukhov M., Soshinskaya E., Mozhaev AA, Klinov D., Schäffer T., Shtykova E., Batishchev O. Spatial organization of Dps and DNA–Dps complexes // Journal of Molecular Biology. 2021. Vol. 433. No. 10. P. 166930. doi
- Article Dadinova L., Kamyshinsky R., Chesnokov Y., Mozhaev AA, Matveev V., Gruzinov A., Vasiliev A., Shtykova E. Structural Rearrangement of Dps-DNA Complex Caused by Divalent Mg and Fe Cations // International Journal of Molecular Sciences. 2021. Vol. 22. No. 11. P. 6056. doi
- Article Petoukhov M., Konarev P., Volkov V., Mozhaev AA, Shtykova E. The Ambiguity Issue in Solving Inverse Problems of Small-Angle Scattering: A Consistent Approach Using an Insulin Receptor-Related Receptor as an Example. Methods for Interpreting SAXS Data // Biochemistry, Supplemental Series A. 2021. Vol. 15. No. 3. P. 270-283. doi
- Article Soshinskaya E., Dadinova L., Mozhaev AA, Shtykova E. Effect of Buffer Composition on Conformational Flexibility of N-Terminal Fragments of Dps and the Nature of Interactions with DNA. Small-Angle X-Ray Scattering Study // Crystallography Reports. 2020. Vol. 65. No. 6. P. 891-899. doi
- Article Goryashchenko A., Mozhaev AA, Serova O., Erokhina T., Orsa A., Deyev I., Petrenko A. Probing Structure and Function of Alkali Sensor IRR with Monoclonal Antibodies // Biomolecules. 2020. Vol. 10. No. 7. P. 1060. doi
- Article Mozhaev AA, Orsa A., Deyev I., Shvets V., Petrenko A. Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain // Doklady Biochemistry and Biophysics. 2019. Vol. 485. No. 1. P. 101-103. doi
- Article Kamyshinsky R., Chesnokov Y., Dadinova L., Mozhaev AA, Orlov I., Petoukhov M., Orekhov A., Shtykova E., Vasiliev A. Polymorphic Protective Dps–DNA Co-Crystals by Cryo Electron Tomography and Small Angle X-Ray Scattering // Biomolecules. 2019. Vol. 10. No. 1. P. 39. doi
- Article Dadinova L., Chesnokov Y., Kamyshinsky R., Orlov I., Petoukhov M., Mozhaev AA, Soshinskaya E., Lazarev V., Manuvera V., Orekhov A., Vasiliev A., Shtykova E. Protective Dps–DNA co‐crystallization in stressed cells: an in vitro structural study by small‐angle X‐ray scattering and cryo‐electron tomography // FEBS Letters. 2019. Vol. 593. No. 12. P. 1360-1371. doi
- Article Mozhaev AA, Serova O., Orsa A., Deyev I., Shvets V., Petrenko A. The Hybrid Protein of the Alkaline Sensor IRR and the Fluorescent Protein GFP Retains the Functional Activity of the Receptor // Russian Journal of Bioorganic Chemistry. 2019. Vol. 45. No. 2. P. 179-182. doi
- Article Shtykova E., Petoukhov M., Mozhaev AA, Deyev I., Dadinova L., Loshkarev N., Goryashchenko A., Bocharov E., Jeffries C., Svergun D., Batishchev O., Petrenko A. The dimeric ectodomain of the alkali-sensing insulin receptor–related receptor (ectoIRR) has a droplike shape // Journal of biological chemistry. 2019. Vol. 294. No. 47. P. 17790-17798. doi
- Article Zubkov E., Morozova A., Chachina N., Shayahmetova D., Mozhaev AA, Deyev I., Chekhonin V., Petrenko A. Behavioral Characteristics of Mice with Knockout of the IRR Alkali Sensor Gene // Neuroscience and Behavioral Physiology. 2018. Vol. 48. No. 4. P. 483-487. doi
- Article Mozhaev AA, Erokhina T., Serova O., Deyev I., Petrenko A. Production and immunochemical characterization of monoclonal antibody to IRR ectodomain // Russian Journal of Bioorganic Chemistry. 2017. Vol. 43. No. 6. P. 653-657. doi
- Article Shayahmetova D., Zhevlenev E., Mozhaev AA, Deyev I., Petrenko A. Genetic link between IRR-receptor and Ly6/PLAUR protein // Russian Journal of Bioorganic Chemistry. 2016. Vol. 42. No. 4. P. 449-452. doi
Employment history
M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry RAS
Senior research fellow 2023 - present
Research fellow 2018 – 2023
Junior research fellow 2015 – 2018
Federal Scientific Research Centre “Crystallography and Photonics” RAS
Research fellow 2020 – present
Junior research fellow 2017 – 2020
Pirogov Russian National Research Medical University
Research fellow 2021 – present
National Research University Higher School of Economics
Associate professor 2022 – present